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Description
Theoretical concerns regarding thyroid cancer stem from rodent studies showing increased medullary thyroid carcinoma with GLP-1 agonists

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Hicks, J
LBA 57 Wang, L

It simply takes an existing biological signal, GLP-1, and makes it last long enough to produce meaningful effects

How GLP-1Based Compounds Influence Appetite and Reward Pathways GLP-1 receptor agonism affects multiple physiological systems: Delays gastric emptying Enhances satiety signaling Reduces appetite-related signaling Modulates central nervous system pathways involved in reward and motivation Within the central nervous system, GLP-1 signaling interacts with reward circuits , including pathways associated with dopamine transmission
