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The number that launched it came out of the semaglutide STEP 1 trial, where a body-composition substudy found that close to 40 percent of the weight people lost showed up as lean mass on the scan (Wilding et al., 2021)

Taylor R, Al-Mrabeh A, Zhyzhneuskaya S, et al

Exendin-4 attenuates renal tubular injury by decreasing oxidative stress and inflammation in streptozotocin-induced diabetic mice

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