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In recent years, GLP-1RAs have become well-established therapies in T2DM

The American Diabetes Association 2026 Standards of Care provides guidance on selecting appropriate glucose-lowering therapy based on cardiovascular, kidney, and metabolic considerations

Currently, the Food and Drug Administration (FDA) has approved seven GLP-1 prescription medications: When used in addition to a reduced calorie diet and increased physical activity , these medications are FDA approved for one or more of the following: Improving blood sugar levels in adults with T2D

For patients who may need both medication and surgery, which one should we recommend first

Injecting cold medication: Administering GLP-1 medication directly from the refrigerator increases injection discomfort and may affect absorption

The long-acting profile of liraglutide and its well-established cardiovascular protective effects make it a preferred therapeutic option for patients with diabetes and coexisting cardiomyopathy [88]