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doi: 10.1111/dom.2011.13.issue-1 211 de LemosJALinetzkyBle RouxCWLaffinLJVongpatanasinWFanLet al

Systematic review design The authors screened various electronic databases to identify clinical trials that investigated the effect of GLP-1 receptor agonists on different types of substance use disorders (alcohol, nicotine, and cocaine use disorders) in adult patients

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GLP-1R activation and artery wall function GLP-1 has pleiotropic effects on the cardiovascular system

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Jungheim and colleagues assessed that despite the superior effect of double treatment with GLP-1RAs and metformin on BMI, IR, visceral adipose tissue, and androgen bioavailability compared to metformin-only treatment, the comparability of these results implies some additional effects of liraglutide on fertility [110]