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In the HARMONY-3 clinical trials (104-week randomized, double-blind, placebo- and active-controlled trial assessing the efficacy and safety of albiglutide compared with placebo, sitagliptin, and glimepiride in patients with T2D taking metformin), the efficacy of albiglutide was examined in patients with T2D which was not controlled by metformin alone therapy

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It has a multitude of functions including the stimulation of insulin hormone which regulates blood sugar by storing energy, the inhibition of the ghrelin hormone which induces appetite, the stimulation of the sympathetic nervous system to increase energy expenditure and slow the movement of the gastrointestinal tract.[10] Below is a visual representation of the effect of the GLP-1 drug on a multitude of body systems.[13] Essentially, GLP-1 drugs like Ozempic, Wegovy, etc

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