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Tirzepatide was the second dual incretin receptor agonist advanced to clinical study

But low may do nothing

Starting at 2 mg and escalating slowly is KEY, as the Phase 2 data showed a lower starting dose of 2 mg produced meaningfully fewer GI side effects than jumping in at 4 mg

[DOI] [PubMed] [Google Scholar] Carel J.-C., Roger M., Ispas S., Tondu F

Miami dermatologist Joely Kaufman, MD says many patients first notice the change once they begin feeling good about their progress
