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Teneligliptin (TEN), a DPP-4 inhibitor, demonstrated mild analgesic effects against acute pain and significant effects against neuropathic pain in a rat model induced by partial transection of the sciatic nerve [36]

[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Pirro V, Roth KD, Lin Y, Willency JA, Milligan PL, Wilson JM, Ruotolo G, Haupt A, Newgard CB, Duffin KL

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Its phase 2 and phase 3 data set spans thousands of participants across the SURPASS and SURMOUNT trial programmes, giving researchers an extensive published literature base against which to calibrate experimental design and expected outcomes