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Published clinical trials have reported large average body weight reductions in obesity protocols, dose dependent HbA1c and weight changes in type 2 diabetes protocols, and liver fat imaging endpoints in defined substudies, which is why retatrutide is now a major reference point in modern metabolic peptide research

She gained nearly 20 kilograms in just 2 months

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Beyond the scale, the same participants saw improvements in blood pressure, cholesterol markers, blood sugar control, and liver fat

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