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NIT-1 cells treated with PA+Ex-4 and PA+GW showed enhanced GSIS capacity, increased PPAR expression, decreased UCP2 expression and ADP/ATP ratio, and improved mitochondrial DNA content and mitochondrial membrane potential compared with those treated with PA alone, whereas the opposite results were observed in the PA+GSK group

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Weight regain was estimated to plateau at 75.6% (95% CI 68.5-82.7) of the weight lost on treatment

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During this period, the monkeys had access to alcohol 4 h per day and free access to water 24 h per day
