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Description
Yes, in some cases

Semaglutide activates only GLP-1 receptors, while tirzepatide (a GLP-1/GIP receptor agonist) engages dual pathways, often producing faster or more substantial weight lossup to 22% in clinical trials versus 15% for semaglutide alone

M., Lehmann, E

Since multi-dose vials are accessed multiple times over several weeks, this preservative is essential for safety

Lancet 402: 613626

Dose and titration speed are among the most significant determinants