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The corresponding plasma concentration was 102,801.74 6627.17 ng/mL and 181,525.94 8838.02 ng/mL after IV and SC injections, respectively
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The drug dampens the dopamine response to reward stimuli

Change in total lean mass Total lean mass (SE) was reduced from an overall baseline of 51.3 kg by 2.3 kg (0.30) vs 1.5 kg (0.28) in the semaglutide and canagliflozin treatment groups, respectively (ETD 0.78 [95% CI 1.61, 0.04]) (Fig

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