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The study did show a reduction in bulimia, or binge-eating with purging, but didnt contain any information specifically about binge-eating disorder, where people dont purge, or anorexia, where people restrict calories

Some noise can return as your body adjusts to a dose, or once youve been on a steady dose for a while

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Dosage & Administration Administered as a once-weekly subcutaneous injection, Use exactly as directed by your prescribing provider, Do not increase dose without medical guidance, Inject into abdomen, thigh, or upper arm, Rotate injection sites If a dose is missed: Take within 48 hours when possible, Otherwise resume next scheduled dose Precautions Tell your provider if you: Have diabetes or eye disease, Have kidney or pancreas problems, Take other prescription or OTC medications, Have mental health history including depression, Do not discontinue treatment without consulting your provider

Either way, if you notice a return of depressive symptoms while losing weight on tirzepatide, do not assume it means the medications are interacting poorly

The logic here is that if the medication causes a wave of fatigue or mild stomach upset shortly after administration, you might sleep through the worst of it