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Long-term success will depend on clinical differentiation, real-world evidence, payer value, patient support programs, adherence tools, physician education, and clear positioning across obesity, type 2 diabetes, cardiovascular risk and metabolic syndrome

This pleiotropic efficacy profile has increased GLP-1RA use, with 12% of adults in the United States (US) reporting ever use of GLP-1RAs

This, in turn, enhances self-efficacy and long-term adherence to exercise and dietary interventions, creating a positive feedback loop that indirectly benefits reproductive outcomes

Role of anti-diabetic medications in the management of MASLD

Monitor weight, food intake and activity consistently

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