glp-1 small molecule agonist BioWorld How GLP-1 Receptor Agonists Evolved

According to the websites of these drugs, there are warnings that there may be dose-dependent and treatment duration-dependent risk for C cell tumors at clinically relevant exposures. This has not been studied in humans and, thus far, there are no reports of these findings

Management of hyperglycaemia in type 2 diabetes, 2015: a patient-centred approach

[PMC free article] [PubMed] [Google Scholar] 876.Vilsboll T., Agerso H., Krarup T., Holst J.J

Role of lateral septum glucagon-like peptide 1 receptors in food intake

In support of this, ICV administration of GLP-1 in rats has been shown to attenuate the fasting-induced rise in NPY/AgRP expression and decreases fasting-induced inhibition of POMC/CART expression in the ARC (Seo et al., 2008)

Psychopharmacology 240 , 12871298 (2023)