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A temporary split dosing approach during the transition period, returning to weekly dosing once adapted, can ease this adjustment

What Do You Need to Do While Taking GLP-1 Medications

Summary: Retatrutide, as an investigational peptide injectable, should be refrigerated at 2C to 8C in line with general peptide storage principles, but the definitive storage conditions are set by the trial sponsor and site pharmacist, not a publicly available SmPC

UCLA Health and other recent clinical nutrition resources continue to emphasize that increased protein intake plus resistance training can help preserve muscle mass during GLP-1-supported weight loss
