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Results showed that for the primary outcome, semaglutide significantly reduced MACE risk by 17%, consistent with effect sizes integrated from prior GLP-1 RAs meta-analyses (14), Heterogeneity tests indicated no statistical heterogeneity across studies, and subgroup analyses revealed no interactions, suggesting semaglutide's effect on MACE was unaffected by potential confounders such as age, sex, BMI, race, or eGFR
Potential improvement in fertility and menstrual regularity In PCOS, excess weight and insulin resistance disrupt the delicate hormonal balance needed for regular ovulation
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When you eat, GLP-1 triggers the pancreas to release insulin, which helps move sugar from your bloodstream into your cells
There is also the potential for surgical delays if risk assessment and management planning are not conducted in advance
