glp 1 peer reviewed articles GLP-1 receptor agonists show promise in treating substance use disorders Long-term Success of GLP-1s Hinges

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2.6 Rapid Weight Loss and Lean Mass Weight loss induced by GLP-1 therapy includes both: Fat mass Lean mass Clinical trials suggest approximately 2040% of weight lost may consist of lean tissue if adequate protein intake and resistance training are not maintained. Reduced lean mass and inadequate protein intake may indirectly influence: Iron status Zinc intake B vitamin intake This secondary pathway reduced dietary density during rapid weight loss is a central nutritional consideration and will be explored in detail in the next section

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doi: 10.1038/s41598-023-34070-6

The answer, he says, is yes. The new results represent an undeniable setback, says Paul Edison, a neuroscientist at Imperial College London who was not part of the work