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Expected weight loss with the -enatides is only around 34 pounds, which is far less than with -glutides

doi: 10.1210/jcem.86.9.7814 186 BedogniGGrugniGTringaliGMarazziNSartorioA

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By 2000, seven studies had been published on the acute effect of peripheral GLP-1 administration on ad libitum energy intake

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Murielle Veniant-Ellison, who heads Amgens obesity research and development, said that in addition to the drug binding to the GLP-1 receptor, its antibody also targets the GIP receptor, like tirzepatide