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Therefore, this review aims to synthesize current evidence on the use of GLP-1 RAs in women planning pregnancy, evaluate emerging safety data, and discuss practical clinical approaches for managing these patients

Some anti-inflammatory effects appear independent of weight loss, which is why microdosing is being explored for RA patients who aren't significantly overweight but have signs of metabolic inflammation

A conceptual review of factors associated with weight loss maintenance and weight regain

High dropout rates in obesity and diabetes trials highlight tolerability issues, which may be further compounded in psychiatric populations where comorbid anxiety, cognitive impairment, or poor illness insight can interfere with consistent medication use

By facilitating glucose-dependent K ATP channel closure and by enhancing CICR, GLP-1 restores the Ca 2+ signal, thereby allowing GSIS to occur

SundstromLMyhreSSundqvistMAhnmarkAMcCoullWRauboPet al
