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Most compounded preparations tolerate up to 30 days at controlled room temperature (up to 77F / 25C) if the pharmacy specifies, though refrigeration is the default

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Patients who withdrew consent during the study were asked if they were willing to undergo a final end of treatment visit, where final assessments were performed

Additionally, food intake and various dosing conditions, including water volume and dosing schedules, can affect the exposure of oral semaglutide

A formulation change was also mentioned by some reviewers as affecting perceived efficacy