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However, serious adverse effects can occur, including pancreatitis (severe persistent abdominal pain), gallbladder disease, and acute kidney injury (typically related to dehydration from gastrointestinal symptoms)

GLP-1 influences fundamental neurobiological processes such as mitochondrial function, protein aggregation, and synaptic plasticity 70,71,72

In comparison to placebo, liraglutide treatment reduced the prevalence of NAFLD by two-thirds, the amount of fat in the liver by 44%, visceral adipose tissue by 18%, and body weight by 5.2 kg (5.6%) (199)

Other unmeasured factors may still influence risk

The changes we observed might have been underestimated

The dose of this medication may be prescribed at a low level and gradually increased to reduce the chance of side effects