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The medications also influence insulin secretion from the pancreas in a glucose-dependent manner, which is why they were originally developed for type 2 diabetes management

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This FDA-approved method targets chronic weight management by mimicking the GLP-1 hormone, crucial for reducing appetite and promoting sustainable weight loss

doi: 10.1097/00004583-201001000-00006

Lacking the dipeptidyl peptidase-4 (DPP-4) cleavage site, exenatide has a much longer half-life than endogenous GLP-1 [13]