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Notably, co-administration with farnesoid X receptor (FXR) agonists or peroxisome proliferator-activated receptor (PPAR) agonists may enhance lipid metabolism regulation and anti-inflammatory effects, addressing multiple pathogenic pathways simultaneously

Department of Nursing, Asia University, Taichung, 41354, Taiwan

Exendin-(9-39) is a truncated form of exendin-4, a GLP-1 receptor agonist, isolated from the saliva of the gila monster

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3.4 BBR regulates intestinal immunity BBR can significantly reduce the abundance of Proteobacteria , (such as Desulfovibrio, and Enterobacter cloacae) , and inhibit LPS production, as well as prevent serum LPS elevation, regulating intestinal permeability, attenuating insulin resistance and improving metabolic endotoxemia effectively (101)