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Below are the key areas to consider when starting or continuing treatment with these medications

Head-to-head clinical data from the SURMOUNT-5 trial found tirzepatide produced approximately 20% greater weight loss than semaglutide at comparable doses

Baig et al

Physiologically, the secretion of growth hormone (GH) in somatotrophs is stimulated mainly by growth hormone-releasing hormone receptor-Gs signaling and partially by ghrelin receptor-Gq signaling, whereas somatostatin inhibits GH secretion by activating somatostatin receptor (SSTR)-Gi signaling 12,13

These companies generated tens of billions in revenue from these medications while allegedly downplaying severe adverse effects that went far beyond the bloating , constipation , and nausea listed on standard warning labels

Weigh the potential benefits against the potential risks before taking this medication while breastfeeding