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Lipodystrophy in insulin-treated subjects and other injection-site skin reactions: are we sure everything is clear

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In contrast, obesity in adults was thought to result from increased size of adipocytes leading to "hypertrophic" obesity

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Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism

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Reply N Engl J Med

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However, when combined with GLP-1 activity that keeps blood sugar controlled, glucagons other effects come to the forefront: increased metabolic rate, enhanced breakdown of stored fat, and thermogenesis (heat production that burns calories)

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