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In the randomized placebo-controlled HOME trial of 390 adults with type 2 diabetes (de Jager and colleagues, Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency, BMJ, 2010), metformin lowered serum B12 by a mean of 19 percent over 4.3 years

have investigated a possible correlation between airborne metal exposure of female nurses and risk of PD by a large prospective study with a study duration of 18 years (19902008) and involving 121,701 participants from 11 different US states

The European Union has a ban on use of dental amalgam effective January 1, 2025

However, the practical applications of most of these synthetic compounds remain restricted due to their limited administration routes, their narrow administration window for efficacy and their toxicity at high doses or during recurrent usage, making them far from ideal candidates for use by astronauts (172)

Zn (II)-porphyrin-based photochemically green synthesis of novel ZnTPP/Cu nanocomposites with antibacterial activities and cytotoxic features against breast cancer cells

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