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Daleke, 2008) proteins

An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation

The index ranges between 0 (not druggable) and 1 (highly druggable)

doi: 10.1038/nature11551 46 LozuponeCAStombaughJIGordonJIJanssonJKKnightR

In general, the prevalence of CIPN resulting from different antitumor drugs and doses varies significantly, with reported prevalence rates ranging from 19 to more than 85% [17]