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Without a mechanism for sharing the Medicare savings and the program investments, as is built into the ongoing Financial Alignment Initiative demonstrations, states may see little benefit in pursuing DSNP-based integrated care models

Deletion of v8 from neuroepithelial cells or deletion of Tgfbr2 or Tgfb1 in microglia each lead to the same phenotype of profound and progressive motor defects and persistence of dysmature microglia

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