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The high lipophilic property of methamphetamine allows a simple diffusion of drug across the blood-brain barrier

However, compared to genetic mutations targeting known ageing pathways, the typical effect sizes of adult-onset drug interventions are relatively small, even in short-lived model organisms 12

EVs secreted from miR-132-overexpressing ADSCs promote diabetic wound healing by upregulating angiogenesis, collagen deposition, and ECM fibronectin accumulation and attenuating local inflammation through nuclear factor-B (NF-B) signaling-mediated M2 macrophage polarization [96]

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