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Description
Treatment of HCC cells with ADI-PEG20 downregulates the key enzymes of pyrimidine synthesis in the TCA cycle, carbamoyl phosphate synthetase 2, thymine synthase (TS), aspartate transcarbamylase and dihydrooratase (CAD) and malate dehydrogenase 1 (MDH-1) activities, making tumor cells more susceptible to 5-fluorouracil (5-FU)
doi: 10.3389/fmed.2022.1037749
Di Pierro F
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YC got the Program: Medical and health science and technology plan of Zhejiang Province (2021KY920)
Electron avenue: Pahtways of disulfide bond formation and isomerization
