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Copper tripeptide, specifically GHK-Cu or copper tripeptide-1 (glycyl-L-histidyl-L-lysine complexed with copper), has earned its reputation as a gold standard regenerative peptide in professional skincare formulations

doi: 10.1111/j.1365-4632.2004.01993.x

Hopkins AM, Walsh SV, Verkade P et al (2003) Constitutive activation of Rho proteins by CNF-1 influences tight junction structure and epithelial barrier function

[DOI] [PubMed] [Google Scholar] 53.Coll AP, Loraine Tung YC

After 3 days they get used to it and never complain
