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Hep-G2 cells with MIA3 overexpression were subjected to RNA-seq, and the downstream target gene CHAC1 (glutathione-specific -glutamyl cyclotransferase 1) was selected according to the results of the volcano map of gene enrichment

Treatment with HNE, or an increase of endogenous HNE by inhibiting glutathione peroxidase 4, reduced inflammasome activation in mouse models of acute lung injury and sepsis

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Hesperidin : A naturally occurring citrus flavonoid commonly used in nutritional supplements
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