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doi: 10.1016/S0169-409X(02)00029-7
Increased intestinal permeability is a genuine, measurable mechanism that is associated with real disease
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Inflammatory cytokines, which are known to activate ER stress pathways, have been shown to induce both citrullination and deamidation of beta-cell proteins (79, 80), such as GRP78 and proinsulin

Hence, the Identification of RBC molecular mechanisms assists in the development of diagnostic tests, therapies, and transfusions
It is also listed as a prohibited agent by the US Department of Defense/War as well as by the World Anti-Doping Agency (WADA)