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[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Shen Y.C., Fan J.H., Edenberg H.J., Li T.K., Cui Y.H., Wang Y.F., Tian C.H., Zhou C.F., Zhou R.L., Wang J., et al

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Therefore, it seems highly desirable to biosynthesize erinacines using bioreactors to obtain a high yield of mycelia with high concentrations of bioactive metabolites, which can expand mushroom potentialities for the development of functional foods, nutraceuticals, and novel drugs [28]

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They then mature within the microenvironment of various tissues, including the vascular endothelium and the brain, where they participate in both innate and adaptive immune responses, even in the absence of antigen presentation (Dong et al., 2014b)