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A meta-analysis reported an odds ratio (OR) of 0.621 for developing AD in individuals with one ApoE2 allele and 3.68 for those with one ApoE4 allele, compared to individuals homozygous for ApoE3

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[DOI] [PubMed] [Google Scholar] 210.Steiger M.B., Steinauer A., Gao D., Cerrejon D.K., Krupke H., Heussi M., et al

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Examples of polycyclic heteroaryl groups consisting of a heteroaryl ring fused to a non-aromatic ring are described below