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The pronounced protective effect of the ferroptosis inhibitor Fer-1compared to apoptosis or autophagy inhibitorsdefinitively established ferroptosis as the predominant cell death pathway

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Remarkably, the GO@GSH-FA treatment group exhibited a significant amelioration in cell viability compared to the OGD/R group, with cell viability restored to levels comparable to the control group, suggesting that the treatment effectively reversed the detrimental effects of OGD/R (Figure 4C)

Fc-Receptor-Mediated Intracellular Delivery of Cu/Zn-superoxide Dismutase (SOD1) Protects Against Redox-Induced Apoptosis Through a Nitric Oxide Dependent Mechanism, Ioanis Vouldoukis, Virginie Sivan, Marie Catherine Vozenin, Caroline Kamat, Alphonse Calenda, Dominique Mazier, and Bernard Dugas Interaction between physical exercise and antioxidant systems - GliSODin To study the mutual interaction between physical exercise and antioxidant systems in rats, we selected swimming as a model for exercise performance