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Lupeol acetate was reported to perform its wound healing activity through the reduction of NF-K, and MPO, reducing iNOS expression and resulting in reduction of NO [60]

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10.1016/j.ijmm.2013.06.004

Cysteine pKa depression by a protonated glutamic acid in human DJ-1
[32], activation of this pathway suppresses pro-inflammatory cytokine production via NF-B inhibition and promotes the synthesis of prostaglandin D2, which in turn further attenuates NF-B signaling and associated inflammatory cascades [40]
