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The Fenton reaction (Fe 2+ + HO Fe 3+ + OH + OH) generates excessive reactive oxygen species (ROS) that surpass the neutralizing capacity of endogenous antioxidants such as glutathione (GSH) (Long et al., 2020)
To cause moderate ALF, the rats were given a single oral dose of CCl 4 at a concentration of 2.5 mL/kg body weight
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Stable liver function during long-term administration of Eltrombopag, a Thrombopoietin receptor agonist, in patients with chronic liver disease
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