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As OCTN3 mediates sodium-independent carnitine transport and humans lack a functional ortholog of this protein, caution is warranted when extrapolating data on renal carnitine handling from rodent models to humans [78, 79]

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Further exploration of the specific mechanism and intervention measures of sdLDL-C may provide a new direction for clinical prevention, evaluation and treatment of AS

Apr 2021;60(3):1521-1536

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For L-carnitine, rigorous studies focusing on exercise performance and muscle fatigue frequently utilize daily doses ranging from 1,000 mg to 3,000 mg to achieve significant metabolic shifts