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The OCTN2 carnitine transporter mediates high-affinity carnitine transport Defective OCTN2 activity reduces carnitine levels and impairs fatty acid oxidation Missense mutations in OCTN2 define the function of selected transporter domains Defects in carnitine biosynthesis do not reduce carnitine levels Acknowledgments This work was supported in part by NIH grant DK 53824

Le persone con a dieta vegana pu presentare carenze di carnitina perch la maggior parte della carnitina presente nell'organismo fornita da alimenti di origine animale (carne, pesce, uova e latticini)

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Decreased serum carnitine is independently correlated with increased tissue accumulation levels of advanced glycation end products in haemodialysis patients

Additionally, in vitro experiments revealed that Pg upregulated the expression of FMO3