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Prolonged selenium deficiency has been conclusively linked to an elevated risk of various diseases, including but not limited to cancer, cardiovascular disease, inflammatory bowel disease, Keshan disease, and acquired immunodeficiency syndrome
Cao, F., Fu, M., Wang, R., Diaz-Vivancos, P
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Expression levels of PPAR and CYP-19 in polycystic ovarian syndrome primary granulosa cells: influence of -3 fatty acid

Alcohol and metabolic-related HCCs exhibit higher mortality rates potentially due to delayed diagnosis rather than inherent aggressiveness

Tumor-associated macrophages and fibroblasts may secrete IGF to activate IGF-IR in cancer cells thereby promoting chemoresistance and radioresistance [187, 188]
