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doi: 10.1016/j.jsps.2015.04.004

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This is exacerbated by reduced levels of serotonin and noradrenaline within the spinal cord, principally affecting the descending antinociceptive pathways [129,130]

Quick Answer: Women reach a higher blood alcohol concentration (BAC) than men from the same number of drinks because of three measurable biological differences lower total body water percentage (averaging ~49% vs ~58% in men), a lower Widmark r factor (0.66 vs 0.73), and reduced alcohol dehydrogenase (ADH) enzyme activity in the stomach

Aging 13 , 2154721570 (2021)