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10.1111/j.1742-7843.2006.pto_461.x [DOI] [PubMed] [Google Scholar] Xu R., Serritella A
1 Introduction Lenvatinib is a small-molecule tyrosine kinase inhibitor (TKI) that targets multiple receptors, including vascular endothelial growth factor receptors (VEGFRs) 13, fibroblast growth factor receptors (FGFRs) 14, and platelet-derived growth factor receptor (PDGFR) and ( L-Carnitine is a quaternary ammonium compound derived from dietary sources and endogenous biosynthesis
After TMAO treatment, in tumor-associated macrophages, stimulatory markers like MHC-I, MHC-II, and CD86 are upregulated, while the anti-inflammatory marker Arg1 is downregulated (79)
PLA2G2A phospholipase promotes fatty acid synthesis and energy metabolism in pancreatic cancer cells with K-ras mutation
104 In GBM cells, histone H3 lactylation, particularly H3K14/18la, facilitates Wnt/-catenin, NF-B, and PD-L1 expression, thereby enhancing CD8 + T-cell infiltration and contributing to immune evasion in GBM
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