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Description
Targets nicotinamide N-methyltransferase (NNMT)
In all of these cases, a thorough medical evaluation is essential before any B12 supplementation

Mental focus
Q: When should PROBALAMIN be used

Carey RM, Schoeffel CD, Gildea JJ, Jones JE, McGrath HE, Gordon LN, et al

In these individuals it would appear that whilst they were able to exist as relatively healthy individuals, often not knowing that they had methylation associated mutations, some initiating factor such as a prolonged infection, combined with low vitamin D levels resulted in gradual loss of their vitamin B12 supplies leading to the CFS symptomatology being apparent, and the subsequent discovery of their methylation status