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showed that Hx can be used therapeutically to attenuate heme-mediated tissue damage upon severe sepsis in mice (Larsen et al., 2010)

Schizophrenia is also linked to increased oxidative stress in the brain and sulforaphane has been shown to improve symptoms of schizophrenia in a small open-label study

Many patients follow an initial protocol over a few months, then reassess to decide whether to continue, adjust, or transition into a lighter maintenance plan

Separately, in the neuroendocrine compartment, AMH signals via the AMHR2/ALK6 complex to rapidly activate the mitogen-activated protein kinase (MAPK/ERK1/2) pathway in gonadotropin-releasing hormone (GnRH) neurons 66,67

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doi: 10.4161/psb.22455