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This axis integrates nutrient signaling with oxidative stress defence, modulating glucose and lipid metabolism, mitochondrial function, and autophagy to maintain cellular stability

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The GLS2 structures reveal that the activation loop, a motif previously identified to regulate enzymatic activity, assumes a unique conformation and works together with a lid that closes over the active site to lock in the substrate glutamine

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Corresponding to Fitzpatrick skin phototypes IIIVI, people of African, Asian, Middle Eastern and ...