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Nrf2 target genes have been shown to be involved in GPX4 synthesis and function, intracellular iron homeostasis, and lipid peroxidation clearance

They are yellow, orange, and red organic compounds composed of eight isoprene units and characterized by many conjugated double bonds

The plastic growing containers (0.30 0.25 0.15 m, 0.075 m 2 surface area) were covered with a hydroponic solution containing macroelements and microelements in the following concentrations: 1.5 mM NH 4 NO 3 , 0.045 mM K 2 HPO 4 , 0.505 mM KH 2 PO 4 , 1 mM K 2 SO 4 , 3 mM CaCl 2 , 0.5 mM MgSO 4 , 0.4 mM Fe-EDTA, 14 M H 3 BO 3 , 5 M MnCl 2 4H 2 O, 3 M ZnSO 4 7H 2 O, 0.7 M CuSO 4 5H 2 O, 0.1 M Na 2 MoO 4 2H 2 O, and 0.1 M CoCl 2 6H 2 O

Following the DMC analysis, we performed pathway enrichment analysis for KEGG pathways using the gometh function from the missMethyl R package 51

however, IGF1 has actions distinct from those of growth hormone in carbohydrate, lipid, and protein metabolism