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In research, BPC-157 is studied for its ability to protect and repair tissue in animal and lab models

[15] When Waddington coined the term, the physical nature of genes and their role in heredity was not known

Gipp et al., 1995

According to the available information, the possible VCI was defined as having cognitive dysfunction (i.e., a Montreal Cognitive Assessment [MoCA] score 24) combined with common VRFs (e.g., diabetes, hypertension, hyperlipemia, smoking, obesity) or mild to severe vascular brain injury on MRI (simple SVD score 1 [29])

PMID: 38295952

Such long-lasting phenotypic changes, however, can only be sustained when an epigenetic stabilization of gene transcription or programming occurs in the cell population that is capable of self-renewing, is multipotent, and is required in organ development and regeneration [41, 131]