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It activates LCAT (Lecithin-cholesterol acyl transferase), which in turn promotes breakdown of cholesterol-containing lipoproteins

Post-shortage, the FDA enforced restrictions on compounding, halting most sales by May 2025 and issuing warnings against unapproved GLP-1 drugs falsely marketed for weight loss, citing risks of adverse events from non-FDA-approved formulations

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Kurella M, Lo JC, Chertow GM

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At the end of this time, a statistically significantly higher proportion of dogs treated with GLME had shown improvement in their clinical condition (66.7% with GLME compared with 40.5% taking placebo