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When activated, Nrf2 modulates the intracellular oxidative stress response by binding the antioxidant response element (5-TGACXXXGC-3) of genes encoding antioxidant enzymes, enzymes involved in glutathione metabolism, and enzymes involved in the generation of reducing equivalents (Tonelli et al

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Schnurr, K., Belkner, J., Ursini, F., Schewe, T

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doi: 10.1007/s12011-023-04029-9 104 LanYWuSWangYChenSLiaoWZhangXet al

Although this sample size is commonly used in exploratory multi-omics research and yielded statistically significant differences across multiple omics layers, it may not fully capture biological variability